Antidepressant for the guys, pointless and dangerous!

New analysis of old data, overturns the conclusions made 15 years ago: today we know that the paroxetine doesn’t help in curing the depression at the teenagers. And this reverse raises, one more time, the problem of an independent and ‘objective’ valuation of the results taken from drugs.

‘A drug against depression is safe and can be used also from the children and teenagers’. Against order: ‘No! Not just that they don’t serve about anything, but they are also dangerous!’

Opposing views: In 2001 important study have concluded that the molecule could be used for curing the depression also at children, obviously in the area more delicate of the disorder in adults: it was effective and well tolerated.

Now a new analysis made on the same data, on which were based the previous affirmations, made another group of researchers to make exactly opposite conclusions. ‘Nor the paroxetine nor the imipramine in high doses, have not be demonstrated as efficient for the big depression at teenagers, and for both drugs there was an increase of the harmful effects’, write the authors in an article of the British Medical Journal.

The original study: How could happen such a change of course? The original study has examined the depression treatment for 2 months in 3 groups of 90 teenagers that consumed the proxetine, a placebo pill or imipramine, concluding that although there were no significant improvements based on the questionnaire that measures the classic depression, there were no big side effects.

 Original data: The authors of the new research, in which there are psychiatrists that for long time moved allegations of the drug safety besides the data on which is based the study in 2001, have fathomed thousands and thousands of rough medical data and not yet elaborated. In practice, they have read not only the analyzed numbers, but the reports and the medical records of the people who were part of this study. Discovering that the choice on how to measure improvements, or classify certain outcomes and side effects had been subject to a good measure of ‘interpretation’.