Celiac disease can be diagnosed at kids simply with a blood test!

The purpose of the new protocol is to diagnose the disease in the initial phase and to reduce the ‘false positives’, i.e. the incorrect diagnoses.

A growing problem

The cases diagnosed in 2014, have exceeded the quota of 150 000, but it is estimated that many – more than 400 000, in which 50 000 children – remain submerged because of mild, exchanged with other conditions with similar gastrointestinal symptoms. But it is not a question of numbers to stop: the intention of the protocol is to diagnose the disease in the initial phase and to reduce the ‘false positives’, i.e. the incorrect diagnoses, which in terms of health means to the patient minor suffering unnecessary or avoidable discomforts, minor possibilities of incurring of inappropriate cures or in bigger cases of hospitalizations if the diagnose is late, bigger costs for public spending.

The news

The diagnoses for the adults are still unchanged, which is putted under initial monitoring with execution of the serological tests of the blood, targeted to the research by the molecules that are expression of the celiac disease, followed by intestinal biopsy for confirmation of the diagnose. Less invasive are the ‘solutions’ for discovering the disease at the little ones, both in the pediatric age and the adolescence. The endoscopy doesn’t serve anymore for the duodenal sample, but it is enough only the blood test, even with presence of clear symptoms of malabsorption associated to requirements of gluten and if the antibodies, anti-tTG IgA (anti-transglutaminase) and EmA IgA (anti-endomysium), have positive results with levels of at least 10 times higher than threshold. Still, must consist a genetic profile (HLA-DQ2 e/o DQ8), compatible with the celiac disease and a reduction of symptomatology after a gluten free diet.